Society Picks of The Week

Aditxt Inc.
(NASDAQ: ADTX)

Aditxt Inc. (NASDAQ: ADTX) is a biotech innovation company developing technologies focused on mapping and reprogramming the immune system. Aditxt’s immune mapping technologies are designed to provide a personalized immune profile. Aditxt’s immune reprogramming technologies, currently preclinical, are being developed to retrain the immune system to induce tolerance to address rejection of transplanted organs, autoimmune diseases, and allergies.

As further discussed below, the company’s first commercial product is an immune mapping technology, AditxtScore™, which is designed to provide a personalized profile of the immune system.

The company’s preclinical immune reprogramming technology, Apoptotic DNA Immunotherapy™ (“ADi™”), aims to retrain the immune system to induce tolerance, with the goal of addressing vast unmet needs in transplanted organ rejection, autoimmune diseases, and allergies. The company is developing specific ADi™ products for psoriasis, type 1 diabetes, and skin grafting.

Headquartered in Richmond, Virginia, Aditxt also operates locations in Silicon Valley and New York.

AditxtScore™

AditxtScore™ is a proprietary platform designed to provide a personalized, comprehensive profile of an individual’s immune system. The underlying technology, licensed from Stanford University through an exclusive worldwide agreement, offers a highly sensitive and accurate method of detecting and quantifying cellular responses, allowing greater specificity, quantification, and amplification of both clinical and commercial opportunities.

The company’s first commercial application of the platform, AditxtScore™ for COVID-19, delivers timely reports on vulnerability and immune status relating to SARS-CoV-2 and its known variants, giving consumers and physicians the data needed to make informed health decisions. Potential future applications will offer early detection of an array of conditions, including diabetes, cardio-metabolic maladies and hormonal imbalances.

Aditxt’s AditxtScore™ immune monitoring center in Richmond, Virginia, is operational and designed to support the anticipated increased demand for AditxtScore™ as well as related products and services. The company is currently scaling its capabilities at this location, with a goal of processing up to 10 million immune system tests/reports annually.

ADi™

ADi™ is Aditxt’s immune reprogramming platform addressing disease-causing immune responses while maintaining the immune system’s ability to combat pathogenic infection. The company is commercializing a nucleic acid-based technology called Apoptotic DNA Immunotherapy™ (ADi™) which utilizes a novel approach that mimics the way our bodies naturally induce tolerance to our own tissues (therapeutically induced immune tolerance). Aditxt believes its ADi™ technology platform can be engineered to address a wide variety of indications.

Aditxt is currently developing ADi™ products for psoriasis, type 1 diabetes and skin grafting.

Currently, immuno-tolerance is achievable through chimerism and cell-based therapy, but there is a clinical need for a more practical and cost-effective approach which:

• Can be made into a product
• Does not require additional hospitalization
• Is simple to produce and ship

Preclinical studies have demonstrated that ADi™ treatment significantly and substantially prolongs graft survival, in addition to successfully “reversing” other established immune-mediated inflammatory processes. ADi™ treatment is not expected to require hospitalization, instead being delivered as an injection in minute amounts into the skin.

Investment Considerations

• Aditxt is commercializing new innovations with focus on mapping and reprogramming the immune system.
• Aditxt is actively adding distribution channel partners for AditxtScore™ throughout the U.S. and globally.
• The company aims to expand reimbursement coverage for AditxtScore™ for COVID-19 from private insurance and public payers while developing and commercializing tests for other indications.
• Aditxt intends to advance its ADi™ therapeutics pipeline into clinical trials in the coming months, with initial studies targeting psoriasis, type 1 diabetes, and skin allograft transplantation.
• The company is led by a team of experts coming from a variety of different scientific fields and business backgrounds.

- Recent Coverage -

August 23, 2022 11:45 AM

A new study from Rutgers University has revealed that antibiotics can be a double-edged sword when used in early childhood. The study found that even though early exposure to antibiotics can be effective against bacterial infections in early childhood, they also kill off “good” bacteria in the digestive tract. Furthermore, the study found that early childhood exposure to antibiotics can also cause allergies and asthma later in life.

The study, which published its findings in the “Mucosal Immunology” journal, adds to the growing body of research that indicates antibiotic exposure during the early childhood years is associated with the late development of allergies and asthma. In fact, this recent study provides the strongest evidence of this relationship, demonstrating that early childhood use of antibiotics isn’t completely risk free.

Researchers from Rutgers University, the University of Zurich and New York University noted that the use of antibiotic medications by children has a negative effect on metabolic functions and gut microbiome communities. These overall changes in the structure of microbiota can weaken host immunity and make children more susceptible to medical issues as they grow older, the researchers said.

GeoSolar Technologies Inc.

GeoSolar Technologies Inc. (“GST”) is a Colorado-based climate technology company and the creator of the Smart Green Home® system for newly built and existing residences and commercial buildings. The company is focused on revolutionizing the way we heat, cool and power homes with 100% natural energy sources. Its patent-pending integrated system harnesses energy from the earth and sun to power and purify homes and automobiles without the use of fossil fuels.

In a GST home, the sun’s energy is captured on the roof to generate all of the electricity required. Additionally, the consistent climate of the earth is used to keep the home at a perfect temperature year-round, and the company’s proprietary air purifying unit ensures that the air inside the home is safe and healthy.

GST’s home technology has been installed in multiple test homes in Colorado and achieved exceptional results, including some of the most impressive energy efficiency ratings (HERS) in the industry.

GeoSolar Technologies is currently accepting investment as part of a Regulation A+ offering. Everyone* can invest now for as little as $300. For more information, visit the company’s profile on Manhattan Street Capital and review its Offering Circular.

GeoSolar Technologies Inc. (“GST”) has been qualified by the U.S. Securities and Exchange Commission (SEC) to conduct a Regulation A+ capital raise. GST is already a publicly traded company who makes quarterly and annual filings with the SEC and is subject to quarterly PCAOB audits. This is the first time shares of GeoSolar Technologies are being made available for public purchase. Upon completion of this Regulation A+ offering, the company intends to seek a listing of its stock.

Soaring and unstable energy/fuel costs continue to highlight the importance of rethinking the traditional approach to powering homes, from top to bottom. While most everyone is well aware of the remarkable, multi-trillion-dollar opportunity the electric vehicle transformation offers to investors (in addition to the benefits to the climate problem), few recognize that the all-electric home market is as large as electric vehicles and equally important to reducing carbon emissions.

U.S. energy expenditures clocked in at $3,891 per person in 2018, leading to estimated spending of $1.3 trillion on energy that year alone. Despite this, fewer than 3% of U.S. homes are currently powered by solar. This number is poised to increase exponentially as both new and existing residences transition to zero carbon models.

GST estimates that if all the homes in America were powered by its technology, carbon pollution could be reduced by an estimated 1.9 trillion pounds per year, greatly reducing the negative impacts on our climate.

Investment Considerations

• GeoSolar Technologies is focused on revolutionizing the way we heat, cool and power homes with 100% natural energy sources.
• The company’s technology has been installed in multiple test homes in Colorado and achieved exceptional results.
• The GeoSolarPlus system combines solar power, geothermal ground-sourced energy and other clean energy technologies into one fully integrated system.
• The company’s leadership team includes some of the world’s most experienced and respected leaders in the field of decarbonization and sustainable homes.
• GeoSolar Technologies is currently accepting investment as part of a Regulation A+ offering.

- Recent Coverage -

August 18, 2022

GeoSolar Technologies (“GST”), a Colorado-based climate technology company, has sought to address the systemically unsustainable growth in energy demand through the creation of its proprietary SmartGreen(TM), a system designed to harness energy from the earth and sun to power and purify homes and automobiles without the use of fossil fuels. Recent summer heatwaves have caused soaring temperatures that have increased the demand for ways to stay cool. “According to the International Energy Agency, the stock of global air conditioners is set to rise by 163% to over 5.5 billion units by 2050. In fact, the new electricity demand posed by the growing use of air conditioners over the next thirty years alone will be equivalent to the present combined electricity generation capacity of the U.S., EU, and Japan,” explains a recent article. “Through its SmartGreen(TM) Home system, GeoSolar Technologies has sought to address both the issues posed by soaring energy costs as well as the growing carbon emissions crisis. GST’s technology enables a household to capture the sun’s energy to account for all its energy requirements, thereby negating the need to depend on utilities – or be faced with increasingly exorbitant energy bills. Furthermore, SmartGreen(TM) harnesses the earth’s exterior environment to keep the home at a perfect temperature year-round, with the company’s proprietary air purifying unit ensuring that the air inside the home remains safe – an increasingly vital consideration amidst the spread of airborne viruses.”